Top Pictures: intrinsic signal

ScienceDirect.com - Current Opinion in Neurobiology - Lifelong ...

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(a) Intrinsic signal imaging

Optical intrinsic signal imaging in a rodent seizure model

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The spread of optical intrinsic signal (OIS) preceded the EEG spikes in a

pone-0011912-g008: Maps of multiple visual areas recorded with ...

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intrinsic signal optical

ScienceDirect.com - Neuroscience - Functional neocortical ...

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(B) Intrinsic optical signal

f1: Schematic diagram for regulation of cell death by protein ...

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intrinsic apoptosis signal

Intrinsic Signal Imaging of Deprivation-Induced Contraction of ...

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Whisker-evoked intrinsic signal in S1. (A) Stimulation consists of one

Intrinsic Signal Imaging in Macaque Retina Reveals Different Types ...

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Time courses of intrinsic signals evoked by a diffuse flash from six regions

Intrinsic optical signal imaging of glomerular-evoked activity in ...

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Intrinsic optical signal

LeischnerAndorInsight.wmv

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To watch this movie please click "View in Google Picassa" above. Courtesy of Mr Ulrich Leischner at Max Planck Institute of Psychiatry, Munich, Germany - Formalin-induced fluorescence causes a weak and fast fading intrinsic signal, that allows for displaying the shape of cells in biological tissue samples. This signal was often missed because of its weakness and fast fading when recoded with confocal microscopy. The illumination technique Ultramicroscopy can capture this signal, as it illuminates only the section of the sample that is actually imaged. Additionally, as a bright-field technique, it captures all fluorescence coming from the probe. However, the signal is still weak and requires a high-sensitivity camera, such as Andor cameras with em-gain. Image data from a mouse hippocampus CA1. (for details see Leischner et al., PLoS ONE, 2010)

formalin-induced fluorescenceintrinsic signalultramicroscopyixonemccd cameravideo